방광염의 치료

방광염(UTI)의 치료

Treatment of Urinary Tract Infection

Infection Category Antimicrobial Regimen Uncomplicated cystitis Orally 3 days   Local E coli resistance <20% Trimethoprim-sulfamethoxazole DS (160/800 mg) twice daily   Local E coli resistance 20% Ciprofloxacin 250 mg twice daily   or   Norfloxacin 400 mg twice daily   or   Levofloxacin 250 mg daily   or   Gatifloxacin 400 mg daily Complicated/recurrent cystitis Same as above unless culture and sensitivity dictate change   Postcoital Orally once   Trimethoprim-sulfamethoxazole SS (80/400 mg) 0.5 to 1 tablet   or   Ciprofloxacin 250 mg   or   Levofloxacin 250 mg   or   Gatifloxacin 400 mg   Intermittent (begin with onset of symptoms) Same as uncomplicated acute cystitis Mild pyelonephritis Oral 7 to 14 days   Gram-negative Ciprofloxacin 500 mg twice daily   or   Norfloxacin 400 mg twice daily   or   Levofloxacin 250 mg daily   Gram-positive Amoxicillin/clavulanic acid 875/125 mg twice daily Severe pyelonephritis Intravenous until afebrile 24 to 48 hours, then oral to complete 7 to 14 days therapy   Gram-negative Ciprofloxacin 400 mg twice daily   or   Levofloxacin 500 mg daily   or   Gatifloxacin 400 mg daily with or without   Gentamicin 3 to 5 mg/kg/d        OR   Cefoxitin 2 g every 8 hours with or without aminoglycoside        OR   Cefotaxime 1 to 2 g two to four times daily with or without an aminoglycoside   Gram-positive Ampicillin 3 g every 6 hours   or   Piperacillin/tazobactam 3.375 g every 6 hours   or   Ampicillin/sulbactam 3/1.2 g every 6 hours