Antiphospholipid Antibody Syndrome의 진단 기준

Clinical and Laboratory Criteria for Diagnosis of Antiphospholipid Antibody Syndrome

Clinical and Laboratory Criteria for Diagnosis of Antiphospholipid Antibody Syndrome

Clinical criteria   1.    Three or more consecutive spontaneous abortions before 10 weeks (recurrent pregnancy loss); delivery before 34 weeks; one or more unexplained fetal deaths of a morphologically normal infant; or severe preeclampsia or placental insufficiency necessitating delivery before 34 weeks.   2.    Arterial or vascular thrombosis without an obvious precipitating cause; small-vessel thrombosis in any tissue or organ, without significant evidence of vasculitis. Laboratory criteria   1.    Moderate to high levels of IgG or IgM anticardiolipin antibodies.   2.    Detection of lupus anticoagulant. These tests must be positive on at least two occasions at least 6 weeks apart.