Use of heparins during pregnancy (임신중 헤파린의 용량)

Heparin	Dose level	Dosage
LMW heparin	Prophylactic*	Enoxaparin 40 mg SC once daily
		Dalteparin 5000 units SC once daily
	Intermediate•	Enoxaparin 40 mg SC once daily, increase as pregnancy progresses to 1 mg/kg once daily
		Dalteparin 5000 units once daily, increase as pregnancy progresses to 100 units/kg once daily
	Therapeutic	Enoxaparin 1 mg/kg every 12 hours
		Dalteparin 100 units/kg every 12 hours
Unfractionated heparin	Prophylactic	5000 units SC twice daily
	Intermediate•	First trimester: 5000 to 7500 units every 12 hours
		Second trimester: 7500 to 10,000 units every 12 hours
		Third trimester: 10,000 units every 12 hours
	Therapeutic	Dose every 12 hours to keep aPTT at 1.5 to 2.5 times control or patient's baseline six hours after dose